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ALUMNI

Previous postdocs and students from the Arginine Methylation Laboratory

 

Moving on to new pastures, but still very much missed 

POSTDOCTORAL RESEARCHERS

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Dr Agnieszka Zielinska

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After completing her post-doc in the Davies Lab working on the identification of novel PRMT1 substrates in breast cancer and developing state-of-the-art in vivo mouse techniques, Agnieszka is now working as a technical manager at the University of Birmingham.

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Dr Pilar Sanchez-Bailon

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Pilar identified the deubiquitylating enzyme, USP11, as a new PRMT1 substrate and has characterised a role for methyl-USP11 in the repair of double strand breaks by homologous recombination. She is now completing a second post-doc in the Max-Delbrück-Center for Molecular Medicine (MDC), Berlin, Germany.

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Dr Debashish Sahay

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Debashish worked on drug treating breast cancer xenograft models with pre-clinical PRMT5 inhibitors to understand breast cancer stem cell function. He has now moved to the USA to work with Johnson and Johnson Pharmaceuticals. 

PhD STUDENTS

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Dr Thomas Clarke

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After completing his PhD in the Davies Lab understanding how PRMT5 regulates homologous-recombination-mediated DSB repair, Tom was awarded an EMBO Long-Term Fellowship to join the lab of Dr Johnathan Whetstine (MGH, Harvard) to work on lysine demethylases and aberrant copy number gains in cancer. He then moved to Dr Raul Mostoslavsky's lab, (MGH, Harvard) investigating acetylation and the DNA damage response. Tom started his own lab with a K99/R01 fellowship at Boston University in Jan 2024

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Dr James Jarrold

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After completing a PhD using quantitative proteomics to understand how PRMT1 functions in breast cancer, James is now working as a post-doc at Warwick University. 

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Dr Krystian Ubych

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School of Chemisty, with Dr. Rob Neely

Krystian completed his PhD in the lab of Dr. Robert Neely and Dr. Francisco Fernandez-Trillo (University of Birmingham) and was involved in studies of DNA methylation using a combination of organic chemistry, enzyme-based methods and fluorescence imaging. During this time, he got an opportunity to explore the epigenetics of cancer with the Davies lab. 

Dr Matthew Gillespie

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Matthew's PhD studies involved understanding the role of PRMT5 in promoting chemoresistance of breast cancer stem cells. He is now working as a post-doc at Southampton University. 

Dr Elizabeth Dufficy 

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Lizzie completed her iCASE AstraZeneca PhD studentship studying the dynamic modulation of PRMT5 activity after DNA damage. She is now working as a Postdoctoral researcher in Prof. Jason Parson's lab at the University of Birmingham.

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Dr Nicole McFadzean 

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Nicole completed her MIBTP PhD studentship studying the role of arginine methylation in chromatin biology focusing on DNA repair. She also developed a novel approach to isolate asymmetric dimethylated substrates independent of methyl-arginine antibody enrichment.  

A selection of our student researchers

Chloe Martin - MRes Cancer Sciences
Emily Prowse - MSc Clinical Oncology
Jemma Holland  - MSci (rejoined the lab as a technician)

Paige Shaw - MRes Cancer Sciences (went on to a PhD at University of Birmingham)
Charlie Brockwell - Intercalating Medic into the BMedSc programme
Fiona Black - 
Undergraduate professional training year (Cardiff University) (now undertaking a PhD at UCL)
Hannah Rouse - MSci (went on to a PhD at Barts Cancer Institute)
Zac Sandy - MRes Cancer Sciences (went on to a PhD at the University of Manchester)
Lisa Pfeuffer (ERASMUS student from Germany) (now undertaking a PhD at Munich)
James Van Hear - MSci (went on to a PhD at KCL)
Wendy Allen - MSci (went on to a PhD at University of Birmingham)
Summik Limbu - MSci (went on to a PhD in Bioengineering at Imperial and is now a lab manager)

Chowmia Muraleetharan - MSci

Lauren Pitt - MRes Cancer Sciences
Sophie Ord - MRes Cancer Sciences

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